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doi: 10.1016/j.ebiom.2020.102769 219

Aging Cell 2014;13, 379-390, doi:10.1111/acel.12185

The N-methylhistamine is further broken down with the MAO-B enzyme, forming N -methylimidazole acetaldehyde.[ref] Histamine (from body cells) [HNMT enzyme] N-methylhistamine [MAO-B enzyme] N-methylimidazole acetaldehyde Note that the HNMT enzyme (histamine N-methyltransferase) facilitates the transfer of a methyl group in the breakdown of histamine through this pathway