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The soluble fraction was collected by centrifugation, and MgCl 2 (final 5 mM) and 5 units of RQ1 RNase-free DNase I (Promega) were added

Through IVIS analysis, tumors from these mice generated the highest bioluminescence signal among all organs harvested at the same time, which indicated a high amount of Lp-CB localized in tumors following intravenous injection (Fig