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Potency: Roughly 10 times stronger at receptor binding compared to native IGF-1

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In adipocytes, NNMT inhibition elevates NAD and SAM and suppresses de novo lipogenesis in a concentration-dependent manner, consistent with on-target activity [13]

Instead of efficiently storing incoming calories as fat, treated adipocytes become more metabolically active, breaking down stored triglycerides and releasing them for energy use

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