glutathione conjugation wiki

glutathione conjugation wiki Bacterial transferase Glutathione Conjugate - an overview

Name: glutathione conjugation wiki Bacterial transferase Glutathione Conjugate - an overview
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Description

Protection of NRK-52E cells, a rat renal proximal tubular cell line, from chemical-induced apoptosis by overexpression of a mitochondrial glutathione transporter

Barkats M, Millecamps S, Abrioux P, Geoffroy MC, Mallet J

One specific enzyme, GPx4, plays a vital, non-redundant role in protecting the mitochondria

The generation of ferroptosis signals requires the formation of CoA derivatives of PUFAs and their binding to phospholipids, which represents a potential target for treating diseases associated with ferroptosis