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Safety evaluation of AOD9604, a synthetic peptide for use in obesity

Such IGF-1R sub-cellular localization-informed strategies are a promising way to stratify patients for treatment with combinations of rational targeted agents

doi: 10.1182/blood-2014-09-600643 152 StuaniLRiolsFMillardPSabatierMBatutASalandEet al

In a pooled analysis of multiple short-term, placebo-controlled studies of CNS stimulants, psychotic or manic symptoms occurred in approximately 0.1% of CNS stimulant-treated patients compared to 0% of placebo-treated patients