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279, 4272642731.10.1074/jbc.M405127200 25 JezJ

NADPH oxidase is required for glucose-formed NETs and its deficiency caused by aldose reductases competitive NADPH utilisation under high glucose conditions may be the cause of the impaired NET production

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4.2 Imaging 4.2.1 Introduction to imaging techniques for ferroptosis detection Studies combining imaging techniques such as MRI and magnetic nanoparticles for in vivo ferroptosis observation initially emerged in oncology research, where ferroptosis modulation represents a novel treatment approach that potentially overcomes resistance to conventional cancer therapies