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The redox potential of thiol-containing biomolecules is usually doubly pH-dependent

10.1038/mp.2016.189 114 KaushikR.MorkovinE.SchneebergJ.ConfetturaA

Protein oxidative damage in the stratum corneum: Evidence for a link between environmental oxidants and the changing prevalence and nature of atopic dermatitis in Japan

As a result, many women experience: Acne or breakouts Melasma (dark patches on the face) Dry, itchy, or sensitive skin Stretch marks Darkening of nipples, underarms, and inner thighs These changes are normal and usually temporary, but proper care can help manage them safely