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In a second double-blind RCT, KET 0.5 mg/kg IV bolus followed by a 30 min infusion of 0.25 mg/kg/h increased mood and serum brain-derived neurotrophic factor, which is a marker of major depressive disorders and treatment response (Jiang et al., 2016)

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Saltiel AR, Olefsky JM

Oral antibiotics can inhibit the increase of TMAO level after stimulation of the choline or carnitine diet, suggesting that intestinal bacteria are required for TMAO production (Wang et al., 2011

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