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For translation, multi-parameter panels that combine CSF/serum lipid-peroxidation markers (e.g., F 2 -isoprostanes, HNE adducts), protein injury footprints (nitrotyrosine, carbonyls) and compartment-targeted reporters in experimental models (matrix/ER/nuclear H 2 O 2 sensors, peroxiredoxin redox state) and that are aligned to cognitive or motor end-points allow mechanism-anchored evaluation of interventions (Murphy et al

Sugawara T, Chan PH

Manipulation of adenosine kinase affects sleep regulation in mice

22 Posologie et mode d'administration Voie orale placer entre la muqueuse buccale et la gencive pour une administration sublinguale