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Methods: We implemented siRNA and adenovirus-mediated Ybx1 overexpression in primary human and mouse hepatocytes, as well as continuous hepatocytes, to investigate the effect of Ybx1 modulation on PPAR mRNA levels

Environ Exp Bot 77:3343 Gadjev I, Vanderauwera S, Gechev TS, Laloi C, Minkov IN, Shulaev V, Apel K, Inz D, Mittler R, Van Breusegem F (2006) Transcriptomic footprints disclose specificity of reactive oxygen species signalling in Arabidopsis

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10.1038/nrn916 Nat

Cholestatic liver disease: strong evidence In cholestatic conditions, bile doesnt flow properly out of the liver, which can injure liver cells and cause symptoms like itching and fatigue