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Free triiodothyronine (T3) to measure the amount of unbound T3 available

A 2014 mouse study found that NAC and vitamin E accelerated lung tumor progression and reduced survival.41 A 2015 melanoma mouse study found that NAC increased lymph node metastases in mice with malignant melanoma.42 A 2019 mouse study reported that NAC protected against emphysema-related lung damage but also induced lung adenocarcinoma in some mice.43 And a 2021 hepatocellular carcinoma study found that antioxidant supplements including NAC promoted tumor formation, growth, and drug resistance in experimental models by reducing intracellular ROS.3 Newer human data add another layer of complexity

iii) administration of at least one cycle of a chemotherapeutic regimen

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A trial by Florida Atlantic University in 2009 revealed that short-term supplementation of L-carnitine helped 24 fit men perform more powerful sprints on stationary bikes than the control group