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The treatments of these two groups of fistulas are significantly different, CAF are mainly treated with surgery, however, in PFCD, there is extensive evidence supporting a multidisciplinary approach, encompassing medical interventions, surgical procedures, and other newer forms of treatment such as stem cell therapy, which suggests a differing pathogenic basis to PFCD 10

Google Scholar Itzykson R, Kosmider O, Renneville A

Warnings/Contraindications

Barrientos S, Stojadinovic O, Golinko MS, Brem H, Tomic-Canic M

Subcutaneous injections offer significantly superior bioavailability compared to topical application, allowing GHK-Cu to reach deeper tissue layers and exert systemic effects that benefit not only the skin but also hair follicles and broader tissue remodeling internally