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It is challenging to extrapolate findings from animal or in vitro studies and successfully integrate them to produce similar findings in humans, especially with a pathology as intricate as SAH

Gut microbiota metabolites In recent years, significant findings have been made regarding the role of gut microbiota metabolites in the pathogenesis of MASLD

[DOI] [PubMed] [Google Scholar] 44.Saunthararajah Y

In vitro experiments have demonstrated that uric acid can cause vascular endothelial cell injury by activating the NLRP3/IL-1 signaling pathway or Nicotinamide adenine dinucleotide phosphate (NADPH) enzymes (17)