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Some patients report general wellness improvements with weight loss and metabolic stabilization, which can indirectly reduce joint stress

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They depend of the size, hydrophobicity and other physico-chemical properties (Figure 1)

As we explained in the CY 2005 OPPS final rule (69 FR 65775), we generally use the lowest APC payment rate applicable for use with the nominated device when we assess whether a device meets the cost significance criterion, thus increasing the probability the device will pass the cost significance test