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In COPD studies, GHK-Cu at 10 nanomolar concentration restored lung fibroblasts ability to contract and restructure collagen, a function that is severely compromised in COPD patients

Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

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In contrast induced nephropathy (CIN), SIRT1 activated by calorie restriction was able to reduce kidney damage via the modulation GPX4 ( 3.6 Bone health SIRT1 plays an important role in maintaining bone health by regulating ferroptosis

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