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Common side effects are typically mild and short-lived: A warmth or flushing sensation , especially from magnesium and calcium

Selenium substitution has no direct effect on thyroid hormone metabolism in critically ill patients

These reactions are usually short-lived and subside with continued use

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Future Directions: Clinical trials are needed to determine whether safe low-cost dietary supplements, using combined VD+LC, have the potential to alleviate elevated AChE, oxidative stress, and inflammation levels, thereby halting the onset of AD