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Description

Without exposure of the lamina propria to gliadin and the prevention of gliadin and gliadin fragments from entering into systemic circulation, the inflammatory immune reaction typically seen in patients with celiac disease can be averted

Poe FL, Corn J

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PMID: 37921175

However, the systemic introduction of ARA-290 in OIR mice seemed to lower the levels of pro-inflammatory cytokines like IL-1 and TNF- in the retinal tissue, hinting at its possible anti-inflammatory properties