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27 Blocking Hsp90 produces a multi-directed beneficial method since Hsp90 proteins are associated with numerous transcription factors and kinases, particularly NF-B

Although eugenol is classified as GRAS at low doses, doseresponse relationships and long-term safety profiles in MASLD conditions are not well defined, especially considering reports of hepatotoxicity at high concentrations therefore further research is required to enhance its safety profile [178]

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