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Myotube-derived exosomes participate in the transport of irisin and enter osteoblasts through vesicle-mediated endocytosis, which may serve as a novel mechanism for exercise to ameliorate osteoporosis

The reaction of samples at a consistent temperature requires for equilibrating all reagents to room temperature before the assay, including tested samples

Mol cell 82:23152334 Ivanov MP, Ladurner R, Poser I, Beveridge R, Rampler E, Hudecz O, Novatchkova M, Heriche JK, Wutz G, van der Lelij P et al (2018) The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion

While genetic, epigenetic, and molecular signaling mechanisms in EC physiology and pathophysiology have been extensively explored, the crucial role of EC metabolism in EC dysfunction and atherogenesis remains largely understudied

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