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A good example of a PUFA lipoxygenase-peroxidation secondary end product that regulates the survival or the death of cells is 4-hydroxynonenal (4-HNE)

8 Glaucoma Protection Research shows that glutathione levels are significantly reduced in the aqueous humor of glaucoma patients, including both Normal Tension Glaucoma (where eye pressure stays within the normal range) and Primary Open-Angle Glaucoma (where eye pressure remains above normal)

Lancet 2:11701172 Bjornara KA, Dietrichs E, Toft M (2014) Clinical features associated with sleep disturbances in Parkinsons disease

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