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2.5 Serum renal function tests Renal function was assessed by measuring serum creatinine, urea, and uric acid, using commercially available diagnostic kit (Randox Laboratories Ltd., Crumlin, County Antrim, UK)

Increase in -glutamylcysteine synthetase activity as a mechanism for butylated hydroxyanisole-mediated elevation of hepatic glutathione

The limitation here includes that it could not be clearly elucidated the distinction between apoptosis and cell cycle arrest as a primary mechanism of cell growth inhibition by GSTP-silencing, although induction of both of them could be observed in PANC-1 cells (Fig