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Notably, the effects of TSA were independent of -adrenergic stimulation (for example, isoproterenol), NO donor (for example, sodium nitroprusside), protein kinase A inhibitor (for example, H-89 dihydrochloride) or soluble guanylate cyclase inhibitor (1H-[1,2,4]Oxadiazolo[4,3-a] quinoxalin-1-one), indicating its direct and specific action on channel dynamics (134)

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3.3 The impacts of IF on hormonal changes 3.3.1 Growth hormone GH secretion is regulated by several factors, including stress, physical activity, nutrition, sleep, and endocrine feedback mechanisms