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The standard cycle is four to eight weeks of daily dosing followed by a two to four week rest period

Tatemoto K, Rkaeus A, Jrnvall H, McDonald TJ, Mutt V

172 Each of these aspects can influence the mechanical properties of the ACL and its ability to withstand the stresses encountered during physical activities, making them critical considerations in both the prevention and rehabilitation of ACL injuries (Table 4.)