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The shelf life varies by specific product, and all medications should be used before the expiration date printed on the packaging when stored according to the manufacturer's instructions: Semaglutide (Ozempic, Wegovy) : Unopened pens may be stored in the refrigerator until the expiration date on the label Dulaglutide (Trulicity) : Remains stable when refrigerated until the printed expiration date Liraglutide (Victoza, Saxenda) : Maintains potency when refrigerated continuously until expiration Tirzepatide (Mounjaro, Zepbound) : Stable under refrigeration until the manufacturer's expiration date Exenatide (Byetta, Bydureon BCise) : Requires refrigeration and remains effective until expiration when stored properly It is important to note that permitted room-temperature storage periods as specified in the prescribing information do not invalidate the expiration date

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She states that in one of her published Phase 2 clinical trials, 100% of subjects receiving retatrutide experienced significant weight loss at doses of 8 mg/week and 12 mg/week

*Correspondence: Yougen Chen, [email protected] Wang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers