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Both MMA and homocysteine can also be elevated in renal impairment.[7] Once vitamin B12 deficiency is diagnosed, oral, sublingual, or IM 1000-2000 mcg of vitamin B12 administration is appropriate

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10.1080/13880209.2021.1917629 Summary Keywords pulmonary hypertension, natural products, immuno-metabolic crosstalk, vascular remodeling, metabolic reprogramming Citation Ma J, Cao X, Yang X, Zhu Y, Wang H, Liu Y, Chen K, Liu X and Zhang C (2026) Natural products targeting the immune-metabolic regulatory network in pulmonary hypertension: mechanisms, classification, and therapeutic prospects

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