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Inflammatory mediators, including IL-1, TNF-, MMP-13, and p38 MAPK, were significantly downregulated, indicating reduced inflammation and extracellular matrix degradation

doi: 10.3390/IJERPH18041464 81

Summary Keywords appetite, cachexia, cancer, canine, feline, food, nutrology Citation Amaral AR, Finardi GLF, Marchi PH, de Oliveira NMC, Prncipe LA, Teixeira N, Pappalardo MCF, Lima LOC, Cirillo JV, Balieiro JCC and Vendramini THA (2025) Connection between nutrition and oncology in dogs and cats: perspectives, evidence, and implicationsa comprehensive review

A clinical study observed an increase in the intracellular and mitochondrial oxidative stress and decreased antioxidant enzymes

The use of the CRISPR/Cas9 system makes it possible to introduce targeted mutations into various parts of the Or gene and to identify the parts of the gene where the changes would lead to an increase in carotenoid accumulation