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In a paradox of physiology, however, the dysregulation of this very process is a well-established contributor to the pathogenesis of numerous disorders, including cancer and diabetic retinopathy (314)

Once in the bloodstream, MCP acts as a gentle, natural chelating agent

doi: 10.1038/sigtrans.2015.4 22 OBrienJHayderHZayedYPengC

Coelomic fluid of Lumbricus rubellus enhances anti-prolioniferative effect of 5-fluorouracil by modulating focal adhesion kinase express and IL-1b of colorectal cancer in mice

Therefore, developing combination strategies that integrate multiple therapeutic modalities with immunotherapy has become a key approach to improving antitumor outcomes