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[DOI] [PubMed] [Google Scholar] 91.Scholler P., Nevoltris D., de Bundel D., Bossi S., Moreno-Delgado D., Rovira X., Mller T.C., El Moustaine D., Mathieu M., Blanc E., McLean H., Dupuis E., Mathis G., Trinquet E., Daniel H., Valjent E., Baty D., Chames P., Rondard P., Pin J.P

In C2C12 myotubes and skeletal muscle from obese mice, capsaicin upregulates sarco/endoplasmic reticulum Ca 2+ -ATPases (SERCA1/2) and ryanodine receptors (RYR1/2), thereby activating ATP-consuming Ca 2+ futile cycles that recycle Ca 2+ across the sarcoplasmic reticulum and dissipate energy as heat (13)