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Fluorescence microscopy showed, again, the formation of cytoplasmic foci at 10 nM ASO concentration, of nuclear foci at 25 nM as well as the formation of nuclear filaments at 100 nM (Fig

Micro-dosing addresses this concern by providing intermittent gentle stimulation rather than constant maximum activation

Mechanisms of ageing and development, 2017, 166: 6-15

Lean control animals did not show the same fat reduction outcomes, which has direct implications for how researchers frame translational relevance to non-obese models or populations