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Like the glands in humans, the glands of animals provide the building blocks of important hormones

Independently of its function in the -secretase complex, PSEN1 itself is required for complete lysosomal acidification 108,117,118

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LCA supplementation increased the transcription of GLUT4, PKM2, and PDK4, whereas decreased PFKM transcription in obese mice (Figure 5K)