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Functions as a for metabolic reaction required for synthesis of purines and pyrimidines: co-enzyme The reaction depends on methyl cobalamin as a co-factor and is also dependent on folate, in which the methyl group of methyltetrahydrofolate is transferred to homocysteine to form methionine and tetrahydrofolate

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The results aren't dramatic week to week

Start slowly, patch test when trying a new product, and avoid applying to irritated or broken skin

In the study by Mehta et al (Mehta A), children with congenital isolated GH deficiency demonstrated growth retardation as already at 6 months of age (26 10 SD and 22 13 SD in weight and length, respectively) prior to starting treatment