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50 & Target IC50: GSH [1] In Vitro Glutathione ethyl ester (5 mM) reduces the intracellular reactive oxygen species (ROS) content, promotes meiotic progression, increases the proportion of oocytes with mature cytoplasm (evenly dispersed cortical granules), and improves the normal fertilization rate, blastocyst development rate, and the proportion of diploid blastocysts when treating oocytes from aged cows [1]

Effect of GPX4 on proliferation and metastasis of renal clear cell carcinoma and its relationship with expression of IGF-1R and COX-2

Tyrosine kinase activity of a chimeric insulin-like-growth-factor-1 receptor containing the insulin receptor C-terminal domain

Notably, NAC supplementation even to older animals decreased the lifespan (Fig

Materials and Methods Test Compounds All compounds including astemizole, chlorpromazine, chloroquine, clomipramine, desipramine, fluoxetine, imipramine, nortriptyline, paroxetine, sertraline, thioridazine, dimethylsulfoxide (DMSO), bafilomycin A (BFA) and rapamycin were purchased from Sigma Aldrich (St