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These effects were generally mild to moderate in intensity and were most frequent during the dose escalation period, becoming less common as participants remained on their maintenance dose

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Our results showed that in Loperamide induced constipation, the expression of ChAT protein as well as the number of ChAT positive cells in muscularis propria of colon tissue were diminished

51,52 These interventions promote healthy lifestyle changes by modulating emotions, enhancing self-control, and providing a supportive environment, thereby contributing to effective obesity management