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During the recruitment appointment and subsequent follow-up appointments at six and twelve months, the clinical status and mental health of all volunteers were evaluated, peripheral blood samples were collected, 45 plasma biomarkers (cytokines, chemokines, and growth factors) were assessed, and a comprehensive investigation was conducted using neuropsychological and ophthalmological tests, PET-CT, and magnetic resonance neuroimaging

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Protocol 2: BPC-157 plus TB-500 combination (moderate to severe herniations) Goal: Comprehensive disc repair combining local tissue protection with systemic healing support for more significant herniations or cases that have not responded to single-peptide approaches

Nonetheless, healthcare providers may monitor for any signs of reduced efficacy over the long term

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