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Furthermore, we explored the leading causes of deaths and DALYs attributable to tobacco in 1990 and 2017, which could improve the focus of our tobacco control program

TS induced vascular endothelial dysfunction has been shown to be mediated by the deleterious properties of TS, primarily those relating to reactive oxygen species (ROS) content (Naik et al., 2014), nicotine, and oxidative stress derived inflammation, in a dose-dependent manner (Gill et al., 1989

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