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rxlist.com Phenelzine (Nardil ) Keywords VMAT-2 Inhibitors Reserpine Trade Name: generic Drug Class: Antihypertensive (monoamine depletor) Mechanism of Action: An essentially irreversible inhibitor of the monoamine vesicular monoamine uptake transporters (VMAT1 & VMAT2)

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doi: 10.1186/s12967-016-1010-x

Through NRF2-driven GSH synthesis, tumor cells are protected from oxidative stress, which contributes to chemotherapy resistance by reducing the cytotoxic effects of ROS generated during treatment