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Alcoholism impairs B12 status, so counsel on alcohol use

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

In the second step, GSHS catalyzes the synthesis of another intermediate product, acylphosphate, at the C-terminal of the first intermediate -EC

These observations can then be interrogated in advanced human-relevant platforms, including patient-derived iPSC-based cardiac organoids and microfluidic organ-on-a-chip systems, to dissect ferroptosis-associated signaling networks in a controlled environment