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Figure 2 shows the process of discovering treatment-specific PD and omics biomarkers, followed by analytical verification and testing of the biomarkers in additional clinical and nonclinical studies for translational qualification

doi: 10.3389/fphar.2025.1602581 Received 30 March 2025 Revised 25 June 2025 Accepted 29 September 2025 Published 19 November 2025 Volume 16 - 2025 Edited by Paolo Montuschi, Catholic University of the Sacred Heart, Italy Reviewed by Ruo Wang, Shanghai Jiao Tong University, China Dengyun Nie, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, China Updates Copyright 2025 Xie, Chen, Guo, Zeng and He