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Additionally, insulin inhibits microsomal triglyceride transport protein (MTTP) and promotes apolipoprotein B (ApoB) degradation to regulate VLDL production

There is a critical need for non-murine, natural animal models for Alzheimers research as particularly highlighted by the NIH RFA New/Unconventional Animal Models of Alzheimers Disease. The handful of published papers on degus of differing genetic backgrounds yield inconsistent findings about sporadic AD-like pathological features, with notably differing results between lab in-bred degus versus outbred degus

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