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After the RBCs treatment with a higher concentration of diosmin (60 g/mL) and both concentrations of bromelain (30 g/mL and 60 g/mL), compared to the control, a statistically signicant increase in the rotational correlation time of the MSL spin label attached to hemolysate proteins Molecules 2023,28, 2291 5 of 13 was observed (Figure 5)

Previous studies demonstrated that LBP and LBP liposome nanoparticles (LBP-LNP) inhibit chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 (CXCL12/CXCR4) signal transduction, prevent inflammatory response, enhance cellular autophagy, thereby stimulating metabolism and enhancing refractory wound repair in the diabetic foot (137)

doi: 10.1155/2018/1756308 74 SichettiMDe MarcoSPagiottiRTrainaGPietrellaD

Sarma H, Islam NF, Prasad R, Prasad MNV, Ma LQ, Rinklebe J (2021) Enhancing phytoremediation of hazardous metal(loid)s using genome engineering CRISPRCas9 technology