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They are particularly beneficial for older adults and those with conditions that impair B12 absorption

However, it is important to consult a healthcare provider if the taste persists for more than a few days, or if it's accompanied by other symptoms such as fatigue, weight loss, or changes in appetite

[10] Because pernicious anemia is due to a lack of intrinsic factor, it is not preventable

As mentioned above, some researchers suspect that the biotin deficiency that occurs during B12 therapy might be the cause of B12 acne: some people who take B12 experience severe acne, the cause of which has remained a mystery for years

47 Most studies in patients on HD have shown benefits of B12 either on its own or extra benefit when added to other B vitamins (mostly folate)