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When conventional approaches have plateaued without adequate relief, treatments targeting oxidative stress and immune dysregulation offer different therapeutic leverage

A.FagianiF.CrosbyJ.GeorgakopoulosN

We believe our patients have a true form of cutaneous lupus erythematosus whose main dermatological manifestation is pigmentation

GW501516 also disrupted mitochondrial function, leading to cytochrome c release and reactive oxygen species (ROS) generation, although ROS was not responsible for cell death