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Barchiesi F, Lucchinetti E, Zaugg M, Ogunshola OO, Wright M, Meyer M, et al

In addition, in the course of the clinical trial a number of patients treated with the combination of acetyl L-carnitine and propionyl L-carnitine, without simultaneously taking sildenafil, reported experiencing improvements and satisfactory sexual intercourse

That is, we would stop entering patients if, at any time during the study, we estimated that there is more than a 90% chance that the ORR was less than 30%, a constant rate that is slightly above the expected response rate for these patients on other treatments

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