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98 In head and neck squamous cell carcinoma (HNSCC), cancer cells expressing Plac1 recruit CD4 T cells via the CXCL11/CXCR3 axis and subsequently induce their differentiation into Tregs through the PVR/TIGIT pathway

Oxidative stress triggers apoptosis in vascular smooth muscle cells, reshapes the extracellular matrix (ECM), and governs ECM degradation and remodeling, subsequently impacting aortic compliance

This condition may be induced by a wide variety of environmental stresses and artificial harsh conditions [19- 21]