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[84] Unless indicated otherwise, the following effectiveness ratings are indicative of clinical effectiveness two weeks after the second dose

[21] When treated with cyanocobalamin, patients with Leber's disease may develop serious optic atrophy, possibly leading to blindness, based on few case reports

Results, reported in 2007, showed no statistically significant difference between AOD-9604 and placebo for the primary endpoint of weight reduction at 24 weeks

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