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The forehead, frown lines between the eyebrows, and crows feetthe wrinkles around the eyesare common locations for treatment

Furthermore, it is worth noting that EV preconditioning not only influences biological function but may also exert dual effects on immunogenicity and in vivo biodistribution

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The genetically-encoded biosensor proved to be versatile, as exemplified by its functionality in a series of evolutionary distant organisms (bacteria, plants and animals), different subcellular localizations (cytosol, mitochondria, chloroplasts) and in combination with nutritional, metabolic, pharmacological and genetic perturbations