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Diamond JP, White L, Leeming JP, Hoh HB, Easty DL

Tian X, Lou S, Shi R (2023) From mitochondria to sarcopenia: role of 17-estradiol and testosterone

Cancer 20 , 398411 (2020)

Glutathione is called the body's master antioxidant: - protects against oxidative stress - has anti-inflammatory effects - supports liver detoxification Deficient glutathione underlies the oxidative stress in aging Here's how to make enough glutathione PMID: 34439468 Glutathione is called the body's master antioxidant: - protects against oxidative stress - has anti-inflammatory effects - supports liver detoxification Deficient glutathione underlies the oxidative stress in aging Here's how to make enough glutathione PMID: 34439468 Glutathione is made of primarily glutamine, cysteine, and glycine, which are amino acids Glutathione synthesis is rate-limited by glycine (PMID: 29559876) Taking N-acetylcysteine (NAC) and glycine has been shown to increase glutathione levels (PMID: 17602868

The reaction is particular for thiol groups and characterized by fast kinetics, making it suitable for measuring thiol concentrations in various biological systems