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Such metabolic rewiring towards increased aerobic glycolysis also formed the basis for -glucan-induced trained immunity of monocytes and was associated with epigenetic histone modifications and increased expression of genes involved in glycolysis triggered by the AKT-mTOR-HIF1 pathway (Cheng et al., 2014

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Nise G Article: GASTROENTEROLOGY

As a potential link between red meat consumption and the increasing risk of cardiovascular disease, trimethylamine-N-oxide (TMAO) has been indicated [8]