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The molecule has become the canonical chemical probe for the entire NNMTmethylationNAD axis and is the foundation for a growing field of methylation-rejuvenation research

Whether in the form of mitochondrial-derived peptide itself or in terms of sORF, mitochondrial-derived peptide is suitable for research as a therapeutic agent (1)

In this context it is important to underline another interesting property of T1 that relies on the modulation of regulatory T cell (Treg) function by acting on signals delivered through TLR in response to pathogen associated molecular patterns (Romani et al., 2007, Montagnoli et al., 2006)

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