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Its tough to say, so we definitely need more hard science to look at that in a more objective way, Spittler said

This helps ensure safe dosing, early identification of imbalances and timely adjustments to the treatment plan

Cell culture Caco-2 cells, a human colorectal carcinoma-derived epithelial cell line, were cultivated in Dulbeccos modified Eagles medium (DMEM)/F12 (Gibco) containing 10% fetal bovine serum (FBS) in a humidified incubator at 37 C, 5% CO 2

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After 24 h of growth, cells were harvested by centrifugation at 5000 g for 5 min at 10C and resuspended in LB medium to an optical density (600 nm) of 0.5